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 Human Anatomy

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The average human body contains enough: iron to make a 3 inch nail, sulfur to kill all fleas on an average dog, carbon to make 900 pencils, potassium to fire a toy cannon, fat to make 7 bars of soap, phosphorous to make 2,200 match heads, and water to fill a ten-gallon tank (Trivia by Brain Candy).
 
 

Human Organ Systems

Miniatlas Cross Section

 

Nervous System 

The nervous system is composed of the brain, spinal cord, nerves, and sensory organs.  It's main function is to coordinate the body's activities, detect all stimuli and form responses to them.  The brain is the control center of the the nervous system.

Human Brain

The Central Nervous System is made up of the brain and spinal cord.  The spinal cord transports sensory and motor  information from other parts of the body to the brain.

The brain only weighs 3 pounds, but is composed of more than 12 billion neurons and 50 billion supporting glial cells. With the spinal cord, the brain monitors and regulates many unconscious bodily processes such as heart rate and breathing, and coordinates most voluntary movements. Most important, it is the site of consciousness and of all the intellectual functions that allow humans to think and create.
 

Click for larger image 

The brain produces electrical signals, which, together with chemical reactions, let the parts of the body communicate. Nerves send these signals throughout the body.

The Nerve Cell

Each neuron consists of a nucleus situated in the cell body, where outgrowths called processes originate from. The main one of these processes is the axon, which is responsible for carrying outgoing messages from the cell. This axon can originate from the central nervous system (CNS) and extend all the way to the body's extremities,  providing an efficient highway for messages.  Dendrites are smaller secondary processes that grow from the cell body and axon. On the end of these dendrites lie the axon terminals, which plug into a cell where the electrical signal from a nerve cell to the target cell can be made. This 'plug' (the axon terminal) connects into a receptor on the target cell and can transmit information between cells.

Autonomic Nervous System (ANS)

The Autonomic Nervous System is divided into 3 parts:

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The sympathetic nervous system

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The parasympathetic nervous system

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The enteric nervous system

It is responsible for regulating muscles and  glands


Spinal Cord Vertebrae

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7 cervical (neck) segments

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12 thoracic segments

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5 lumbar segments

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5 sacral segments

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4 fused coccygeal segment

Brain Activity Human Brain
Brain Atlas Interactive Anatomy
Cell Phones & Brain Cancer Mental Fatigue
Central Nervous System Neurology
Discovering Psychology:The human brain  
Headaches Neuroscience

 

Skeletal  System

Mrs. King - Spirit Week at EGHS 

The skeletal system consists of the bones, tendons, ligaments, and cartilage.  It's main function is to support the body and provide protection for the internal organs. 

Biology 101

 
Interactive Anatomy Physiology in Space
Osteology Skeletons

 

Muscular System

Muscular System

The muscular system  consists of skeletal muscles.  These muscles attach to the skeleton and provide movement and locomotion.  There are 3 main types of muscle tissue as you will see listed below.

           Muscle Tissue

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Skeletal

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Striated

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Cardiac

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Striated

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Intercalated disc

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Smooth

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Involuntary

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Spindle shaped cells

 

 

Integumentary System

Hair, Skin, and Nails

Integumentary System

The integumentary system consists of the skin and its derivatives; hair and nails. This system is the body's first line of defense against foreign invaders and  protects against mechanical injury, infection (disease) and also prevents  the inner organs from drying out by retaining body fluids. Your skin also plays an important role to eliminate waste products, regulate body temperature and protects the body from harmful ultraviolet rays from the sun.

Everyone, young and old, should minimize exposure to the sun and protect themselves from  Ultraviolet Radiation. UVA and UVB rays damage the DNA in skin cells and can lead to deadly forms of skin cancer (Melanoma Carcinoma). Sun exposure increases the fine lines on skin, known as wrinkles, and accelerates the timeline of the aging process.  Prevention is easily achieved by limiting the amount of time you are exposed to UV rays and by using products that help prevent exposure to UVA and UVB rays.  With this said, it is understandable why it is important to take care of your skin! 

Secretions from the sebaceous and sweat glands maintain the pH on the skin's surface at the pH of about 3 to 5. This acidic surface keeps many invaders from making a home on your skin.  Your body's natural flora of bacteria have adapted to this acidic surface.

 

Dermatitis Integumentary System
Histology Skin Care

 

Digestive System

 

Digestive System

 

The digestive system begins at the mouth and ends at the anus.   Consists of mouth, pharynx, esophagus, stomach, intestines, liver, pancreas, and anus.  The main function of the digestive system is to process food through ingestion through the mouth, digestion, in the stomach,  absorption of water and nutrients in the intestines, and elimination through the anus. 

Larynx

Anterior                              Posterior 

   

Gallbladder

Gall Bladder

Biology 101 New Food Pyramid
Digestive System Nutrition & Digestion
Mouth Anatomy Pathophysiology

 

Excretory System

excretory system

Kidney      click for web siteKindney, inferior vena cava, aorta, ureter, urinary bladder

The excretory system is responsible for the disposal of metabolic wastes and the regulation of osmotic balance of the blood.  This organ system consists of the kidneys, ureters, urinary bladder,  and urethra.  The kidneys are bean shaped and lie in the superior lumbar region of the posterior abdominal wall.  The right kidney is crowded by the liver and is slightly inferior to the left kidney.  The average kidney is about the size of a large bar of soap.  The convex portion  of the kidney shown in the photograph is called the lateral portion.  The concave portion is  called the renal hilus.  This is where the renal artery, renal vein and renal pelvis leave the kidney.  The smaller image displays the kidneys, adrenal gland (superior to kidney) which is part of the endocrine system, the inferior vena cava, aorta, ureter, and urinary bladder.  The kidneys filter  waste particles from the blood and send toxins, excess water, and metabolic wastes out of the body in the form of urine, while the useful substances from the filtrate are sent back into the blood.  The three nitrogenous compounds that are eliminated from the body are urea, uric acid and creatinine.  Eliminating wastes is only one job of the kidneys, they also regulate the volume and chemical makeup of the blood by maintaining equilibrium between acids and bases and  between water and salts.

 

 
Excretory System  
Kidney  

 

Respiratory System

The respiratory system consists of the lungs, trachea, and other breathing tubes.  It main function is gas exchange; simply put, the uptake of oxygen and the disposal or removal of carbon dioxide.  When you breath in you inhale the oxygen that the lungs need to re-supply red blood cells with oxygen, which is then transported to the rest of the body.  When you breath out or exhale, you are getting rid of the carbon dioxide that the body is trying to eliminate.  The respiratory system works in conjunction with the circulatory system.

Gas Exchange

Bronchi

Image: Encyclopaedia Britannica, 2008

 

 

Gas Exchange  
Respiratory System  

 

Circulatory  System

Veins and Arteries

The circulatory system consists of the heart, blood vessels and blood.  It's main function is to distribute materials throughout the body.

Blood is a connective tissue,  the ground substance is plasma, and the blood cells are called formed elements. Plasma makes up 55% and cellular/formed elements make up 45%. The three formed elements are erythrocytes, leukocytes and platelets, which develop from a single population of pluripotent stem cells  in the red marrow of bones.  This marrow is found in the ribs, vertebrae, breastbone, and pelvis of the fetus. The pluripotent  stem cells are unique because they have the potential to develop into any type of blood cell or cells that produce platelets.

Erythrocytes (red blood cells)
Transport oxygen and carbon dioxide.

Leukocytes (white blood cells)
Play a major role in our immune and defense system.
 

1. Granulocytes (These are also called 'Myeloid Cells.')
2. Monocytes
3. Lymphocytes

Some sources combine the monocytes and lymphocytes into one category and just call them all 'mononuclear leukocytes.'
bulletGranulocytes include the neutrophils, eosinophils, and basophils (their cytoplasm is often filled with granules). These are the work horses of acute inflammation (and other processes). Make sure you learn the neutrophil. In pathology and immunology, you'll call this same cell the PMN (polymorphonuclear leukocyte). Eosinophils are involved in allergic reactions and parasitic infections.
bulletAnother cell to mention here (although it is NOT a granulocyte) is the Mast Cell. It's very similar to the basophil: both release histamine (and other mediators). Some think that the mast cell is derived from the basophil. Just remember that the basophil circulates and the mast cell is found in peripheral tissues. Other than that, they are quite similar.
bulletMonocytes include the monoctye and the macrophage. The monocytes, like all leukocytes, use the bloodstream to reach the connective tissues.  There, they transform into macrophages, phagocytic cells that possess pseudopods and ingest a wide variety of foreign cells, molecules, and tiny particles of debris.  Once in the tissue, it matures into the macrophage. It can also mature even further into other cells. The monocyte/macrophage is the work horse of chronic inflammation.
bulletLymphoctyes are white blood cells. They originate in the bone marrow and are derived from the same stem cell as the rest of the erythrocytes and leukocytes. These are the T-cells and B-cells that direct the immune system and produce antibodies, respectively. They are the central cells in our cell-mediated and humeral (antibody) defense mechanisms. The B-cell can mature into the plasma cell.

*Know that as a rule of thumb, bacterial infections cause granulocytosis and viral infections cause lymphocytosis. There are exceptions to this, but this is a very basic (and important) concept.

Platelets (thrombocytes)
Important in clotting and scab formation. The mineral calcium, vitamin K, and a protein called fibrinogen help the platelets form a clot.
If your body is deficient in calcium and vitamin K  it will take  much longer for your blood to form a clot.  If these nutrients are missing you could bleed to death.  A scab is an external blood clot that we can easily see, but there are also internal blood clots. A bruise, or black-and-blue mark, is the result of a blood clot. Both scabs and bruises are clots that lead to healing.  Not all blood clots are beneficial.  If a clot forms in a blood vessel it will stop the blood flow (which means the oxygen flow)  to whatever organ it's servicing, i.e. heart attack, stroke. Loss of oxygen to the brain would cause paralysis, brain damage, loss of sensory perceptions or death.

 

Plasma 55%  (Clear substance: about 90% water)

Structure Function
Water

Solvent for carrying other substances

Ions
bullet Sodium
bullet Potassium
bullet Calcium
bullet Magnesium
bullet Chloride
bullet Bicarbonate
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Osmotic balance, pH buffering, and regulation of membrane permeability

Plasma Proteins
bullet Albumin
bullet Fibrinogen
bullet Immunoglobulins (antibodies)
bullet Osmotic balance, ph buffering
bullet clotting
bullet defense
Substances transported by blood
bullet Nutrients (glucose, fatty acids, vitamins)
bullet Waste products from metabolism
bullet Respiratory gasses
bullet Hormones


 

BLOOD PATHWAY
 heart -> elastic arteries -> muscular arteries -> arterioles -> capillaries -> venules -> veins -> heart

BLOOD VESSELS
Arteries take blood AWAY from the heart to other tissues. They carry blood high in oxygen (exception: pulmonary arteries) through  thick, springy walls.  As a result the blood pressure is higher in arteries than in veins. Veins take blood back to the heart and  carry blood low in oxygen and high in carbon dioxide (exception: pulmonary veins).  Their walls are thinner, and lumen is much larger than arteries.  The blood pressure, therefore, is lower in veins.  Connecting arteries and veins are tiny vessels called capillaries where gas exchange occurs.

BLOOD VESSEL STRUCTURE
Tunica Externa (Tunica Adventitia):  outermost layer, areolar connective tissue and largest layer in veins.
Tunica Media: middle layer, circularly arranged smooth muscle fibers and largest layer in arteries.
Tunica Intima: innermost layer - endothelium (simple squamous epithelium) and areolar connective tissue

Vascular System -Three Basic Layers: Tunica Intima (with endothelial lining), Tunica Media (smooth muscle), Tunica Adventitia (outer connective tissue).

Elastic Arteries vessel wall contains large amounts of elastin (a protein fiber). Muscular Arteries diameter ranges from .3mm - 1cm, they have less elastin than elastic arteries, and more smooth muscle in the tunica media.   Arterioles diameter is less than .3 mm, and  tunica media consists of 5 or fewer layers of smooth muscle.  Capillaries have a diameter only slightly larger than the diameter of an erythrocyte, consisting  only of  a tunica intima.  They form capillary bed and are the site for gas and nutrient exchange. Venules collect blood from capillaries.  Veins are formed when venules merge together, composed of tunica intima,  and most veins have valves to prevent back flow.

 
  Cardiovascular Pathology
Blood Cardiovascular System
Blood Pressure  Iron
Blood Types & Rh factor The Heart

 

Immune System

Lymphatic System

The immune and lymphatic system consist of bone marrow, lymph nodes, thymus, spleen, lymph vessels, and white blood cells.  It's main function is fighting infection and cancer. better known as the body's defense system.

Nonspecific Defense Mechanisms Specific Defense Mechanisms (immune system)
1st line of defense 2nd line of defense 3rd line of defense
bullet Skin
bullet Mucous membranes
bullet Secretions of skin and mucous membranes
bulletsweat
bullettears
bullet Phagocytic white blood cells
bullet Antimicrobial proteins
bullet The inflammatory response
bullet Lymphocytes
bullet Antibodies

The lymphatic and immune systems are so closely related that we will place them under the same heading.

The main components of the lymphatic system are the lymphatic vessels. Think of the these vessels as the highway in which the disease organisms travel.  It is through the lymphatic vessels that escaped fluid from blood vessels is returned to the blood stream.  These vessels run all through the human body collecting a fluid called lymph.  This fluid travels in a one-way direction toward the heart (due to flap-like mini-valves which prevent backflow)  and empties into the great veins in the base of the neck.  The lymphatic vessels also return leaked proteins from the surrounding blood capillaries back to the bloodstream.  The lymphatic system has no organ (like the heart) to pump lymph through the body, and therefore relies on the pulsing of surrounding blood vessels, body movement and muscle contractions to move or squeeze fluid through the vessels.

The main components of  the immune system are lymphocytes, lymphoid tissue, and lymphoid organs (spleen, lymph nodes, thymus, tonsils, lymphoid nodules in the small intestine, and the appendix).  Think of the lymphoid tissue and organs as the parking garage or battle ground where the disease organisms are detained and ultimately destroyed. 

Artificially Acquired Immunity

Active Immunity Passive Immunity
Development of antibodies in response to stimulation by an antigen Once formed, those antibodies can be removed from the host and transferred into another recipient where they provide immediate passive immunity
Antigens (weakened, dead, or fragments of microbes) are introduced in vaccines. Preformed antibodies in an immune serum are introduced into the body by injection (e.g. anti-venom used to treat snake bites).
The body produces antibodies and specialized lymphocytes. The body does not produce any antibodies.

                             

Body's Defenses Interactive Anatomy
Circulation & Gas Exchange Lymphatic System
Human Immune System Lymphatic System II
Immune System Lymphatic System III

 

Endocrine System

The endocrine system consists of many glands; the pituitary, thyroid, adrenal glands, pancreas, and ovaries/testicles (which also secrete hormones).

A hormone is a chemical substance produced by an animal or plant which acts as a "chemical messenger." Hormones act to help different parts of an organism to function in a coordinated way. Typically, hormones are formed in one part of an organism, and their effect occurs in a different area. The word hormone is derived from Greek and means, "to set in motion."

These chemicals regulate:
Metabolism & growth
Sexual function & reproduction
Production of various blood components
Reaction to stress
Regulation of other hormones

It was not until the early 1900's that the existence of these substances became known. Since then, over 30 human hormones have been identified, and we have developed the ability to extract them from tissues and synthesize them in the lab. In humans, most hormones are produced by certain glands called endocrine glands. Doctors that specialize in the evaluation and treatment of hormone conditions are called endocrinologists.

In humans and animals, hormones control a number of bodily functions including growth, development, and reproduction. In plants, hormones mainly regulate growth. Decreased production of these chemical messengers can lead to serious diseases and even death.

 

Adrenal glands Divided into 2 regions; secrete hormones that influence the body's metabolism, blood chemicals, and body characteristics, as well as influence the part of the nervous system that is involved in the response and defense against stress.
Hypothalamus Activates and controls the part of the nervous system that controls involuntary body functions, the hormonal system, and many body functions, such as regulating sleep and stimulating appetite.
Ovaries and testicles Secrete hormones that influence female and male characteristics, respectively.
Pancreas Secretes a hormone (insulin) that controls the use of glucose by the body.
Parathyroid glands Secrete a hormone that maintains the calcium level in the blood.
Pineal body Involved with daily biological cycles.
Pituitary gland Produces a number of different hormones that influence various other endocrine glands.
Thymus gland Plays a role in the body's immune system.
Thyroid gland Produces hormones that stimulate body heat production, bone growth, and the body's metabolism.

 

 

Reproductive Systems

The reproductive system consists of the ovaries, testes, and other associated organs.  It's main function is reproduction.

Female


 

The cervix is lined with a layer of cells called epithelial cells. Epithelial cells are a general type of cells found throughout the body, and they vary in shape and size depending on where they are. In the cervix, the epithelial cells inside the canal are very different from the cells that line the part of the cervix that borders the vagina. In the canal the cells are tall and are referred to as columnar epithelium. On the outside wall of the cervix, where the cervix meets the vagina the epithelial cells are flat, or squamous. A very delicate area of the cervix is called the squamous columnar junction, where the tall columnar cells end and the flat, squamous cells begin. It is here that pre-cancerous lesions are usually detected and where cells are sampled for Pap smear screening.

Male

The male pelvis is narrower, deeper and has thicker, stronger bones than the female pelvis. The male reproductive glands, testes, lie within the scrotum, which is outside the body between the legs. The testes produce sperm and male hormones. From the testes, sperm pass into a coiled tube called the epididymis where they mature and are stored until ejaculation through the urethra or until reabsorbed by the body. The prostate is about the size of a walnut. It lies just below the urinary bladder and surrounds the upper part of the urethra.
The prostate is an integral part of the reproductive system for men, providing the fluid necessary to transport sperm during ejaculation. However, as men age, the prostate can be a source of problems. Three common diseases of the prostate are: benign prostatic hyperplasia (BPH), prostatitis and prostate cancer. Each of these conditions affects the prostate differently.
 

 
The Eye

 

     External and Internal Eye Anatomy

 

 

The Ear

 

 

Human Diseases

Many foreign invaders such as bacteria, viruses, pathogens in the air, and abnormal body cells can cause disease. Scientists from research and development (R&D) teams all over the world are constantly working on new ways to defeat/control these intrusions.

AIDS

Genes & Disease
Breast Cancer Pathology
Cervical Cancer University Library
Disease Control West Nile
 

 

Other Anatomy Resources

 

Teen Drug Addiction Treatment:
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Florida Addiction Stats and Rehab Support:
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Last modified: July 13, 2014